1-(3-chlorophenyl)-3-[2-(dimethylamino)-2-phenylethyl]thiourea

1-(3-chlorophenyl)-3-[2-(dimethylamino)-2-phenylethyl]thiourea is a chemical compound, often shortened to **CP-105,696** or **CP-105696**. It's a **potent and selective inhibitor of the enzyme acetylcholinesterase (AChE)**.

**Why is it important for research?**

* **Neurological Research:** AChE is a crucial enzyme in the nervous system, breaking down the neurotransmitter acetylcholine. Inhibitors like CP-105,696 can therefore increase acetylcholine levels, making them potentially useful for treating conditions like:
* **Alzheimer's disease:** AChE inhibitors are a mainstay in treating Alzheimer's, helping to improve cognitive function.
* **Myasthenia gravis:** This autoimmune disease affects the muscles, and AChE inhibitors can improve muscle strength.
* **Other neurological disorders:** Research is ongoing to see if AChE inhibitors could benefit other conditions, like Parkinson's disease.

* **Understanding AChE Function:** Compounds like CP-105,696 are essential tools for scientists studying AChE. They help researchers understand:
* The enzyme's structure and function.
* How inhibitors bind to the enzyme and block its activity.
* The potential for developing new and improved AChE inhibitors for treating neurological diseases.

* **Potential for Drug Development:** While CP-105,696 itself is not currently a marketed drug, its structure and activity provide valuable information for the development of new AChE inhibitors with better therapeutic profiles.

**Important Notes:**

* **Toxicity:** CP-105,696 and other AChE inhibitors can have side effects, especially if they cross the blood-brain barrier. Therefore, research and development focus on finding safer and more effective compounds.
* **Clinical Trials:** While AChE inhibitors are used in the clinic, ongoing research is exploring new therapeutic uses for these compounds and developing new inhibitors with better efficacy and safety profiles.

In summary, CP-105,696 is a valuable research tool for understanding AChE function and potentially developing new treatments for neurological disorders.